Vinylogous acids
Medchemexpress LLC Ensitrelvir fumarate | 2757470-18-9 | 100.0% | C26H21ClF3N9O6 | 50 MG
Ensitrelvir fumarate, also known as S-217622 fumarate, is the first orally active, non-covalent, and non-peptidic SARS-CoV-2 3CL protease inhibitor with an IC50 of 13 nM. It demonstrates significant antiviral activity against various SARS-CoV-2 variants, SARS-CoV, and MERS-CoV.
- First orally active, non-covalent, non-peptidic SARS-CoV-2 3CL protease inhibitor
- Inhibits SARS-CoV-2 3CL protease with an IC50 of 13 nM
- Effective against wild-type SARS-CoV-2 and Alpha, Beta, Gamma, and Delta variants with EC50 values around 0.4 μM
- Shows EC50 values of 0.21 μM for SARS-CoV and 1.4 μM for MERS-CoV
- Dose-dependently inhibits intrapulmonary replication of SARS-CoV-2 in mice
eMolecules Ethyl 2-(ethoxymethylene)-4,4,4-trifluoroacetoacetate | 571-55-1 | MFCD00052716 | 1g
Oakwood Chemical | Ethyl 2-(ethoxymethylene)-4,4,4-trifluoroacetoacetate | 1g | 537669984 | 008919 | | 571-55-1 | MFCD00052716 | 240.178 | C9H11F3O4
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Matrix Scientific 3-ETHOXYACRYLOYL CHLORIDE3-E-1
3-ethoxyacryloyl Chloride Mf C5h7clo2 Mw 134.56 Cas 6191-99-7
Sigma Aldrich Fine Chemicals Biosciences 2,5-Dimethyl-4-methoxy-3(2H)-furanone natural, >=98%, FG | 4077-47-8 | MFCD00209504 | 1KG
2,5-Dimethyl-4-methoxy-3(2H)-furanone natural, >=98%, FG | Purity: >=98% | Mol Wt: 142.15 | 4077-47-8 | MFCD00209504 | 1KG
eMolecules Ethyl ethoxymethylene malonate | Oakwood Chemical | 87-13-8 | MFCD00009148 | 216.233 | C10H16O5 | 98.000 | CCOC=C(C(=O)OCC)C(=O)OCC | 500g | 537687906
Ethyl ethoxymethylene malonate | Oakwood Chemical | 87-13-8 | MFCD00009148 | 216.233 | C10H16O5 | 98.000 | CCOC=C(C(=O)OCC)C(=O)OCC | 500g | 537687906
Medchemexpress LLC Boc-val-cit-pab-pnp | 870487-10-8 | 99.6% | 644.67 | C30H40N6O10 | 50 MG
Boc-Val-Cit-PAB-PNP is a protease-cleavable linker used to construct antibody-drug conjugates (ADCs). It releases payloads after intracellular proteolytic cleavage and is supplied as a solid with high purity.
- Cleavable val-cit peptide linker releasing payload upon proteolysis
- Para-aminobenzyl spacer with p-nitrophenyl leaving group
- High purity suitable for research applications
- Soluble in DMSO at 100 mg/mL with ultrasonic assistance
- Recommended storage: -20°C under nitrogen; in solvent store at -80°C for long-term
- Available in small research scales, e.g. 50 mg
Medchemexpress LLC VU0810464 | 2126040-21-7 | 99.3% | 50 MG
VU0810464 is a potent and selective non-urea G protein-gated inwardly-rectifying potassium channels (GIRK, Kir3) activator. It demonstrates nanomolar potency for neuronal (EC50=165 nM) and GIRK1/4 (EC50=720 nM) channels. It exhibits improved brain penetration and reduces stress-induced hyperthermia (SIH) in mice by activating Kir3 channels.
- Potent and selective activator of GIRK (Kir3) channels
- Displays nanomolar potency for neuronal and GIRK1/4 channels
- Exhibits improved brain penetration
- Reduces stress-induced hyperthermia (SIH) in mice
Medchemexpress LLC Adenylosuccinic acid tetraammonium | >98% | 10 MG
Adenylosuccinic acid tetraammonium is an orally active purine ribonucleoside monophosphate involved in nucleotide cycle metabolism. This compound can be converted into fumaric acid via adenylosuccinate lyase and holds potential for the study of Duchenne muscular dystrophy (DMD).
- Orally active purine ribonucleoside monophosphate
- Plays a role in nucleotide cycle metabolism
- Converts into fumaric acid via adenylosuccinate lyase
- Potential for Duchenne muscular dystrophy (DMD) research
- Ameliorates murine Duchenne muscular dystrophy symptoms in vivo
Selleck Chemical LLC 4-Hydroxy-2.5-dimethyl-3(2H)furanone S5178-25mg
4-Hydroxy-2 5-dimethyl-3(2H)furanone (furaneol HDMF) is a naturally occurring substance found in a variety of fruits and has been shown to have antimicrobial activity
eMolecules Zaltoprofen | 74711-43-6 | 1G | Purity: 98%
Combi-Blocks | Zaltoprofen | 1G | 74711-43-6 | MFCD00864323
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eMolecules Ambeed / (R)-4567-Tetrahydro-1H-indazol-5-amine hydrochloride / 100mg / 682930893 / A511997 / / 1291790-29-8 / MFCD18909649 / 173.640 / C7H12ClN3
Ambeed / (R)-4567-Tetrahydro-1H-indazol-5-amine hydrochloride / 100mg / 682930893 / A511997 / / 1291790-29-8 / MFCD18909649 / 173.640 / C7H12ClN3
Accela Chembio Inc 6-bromo-4-hydroxyquinazoline | 5g | 32084-59-6 | MFCD00115131 | 97+% | Shelf Life: 2160 Days | Light Sensitive
6-bromo-4-hydroxyquinazoline | 5g | 32084-59-6 | MFCD00115131 | 97+% | Shelf Life: 2160 Days | Light Sensitive
![eMolecules AstaTech / 7-METHYL-4567-TETRAHYDROPYRAZOLO[15-A]PYRIMIDINE / 0.1g / 722706839 / F53177 / 95.000 / 1260879-61-5 / MFCD13193598 / 137.186 / C7H11N3](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502461930.JPG-250.jpg)
eMolecules AstaTech / 7-METHYL-4567-TETRAHYDROPYRAZOLO[15-A]PYRIMIDINE / 0.1g / 722706839 / F53177 / 95.000 / 1260879-61-5 / MFCD13193598 / 137.186 / C7H11N3
AstaTech / 7-METHYL-4567-TETRAHYDROPYRAZOLO[15-A]PYRIMIDINE / 0.1g / 722706839 / F53177 / 95.000 / 1260879-61-5 / MFCD13193598 / 137.186 / C7H11N3
![eMolecules Pharmablock / 4567-tetrahydropyrazolo[15-a]pyridine-2-carboxylic acid / 25mg / 587659398 / PBT1832 / 0.000 / 307313-03-7 / MFCD09056814 / 166.180 / C8H10N2O2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502515885.JPG-250.jpg)
eMolecules Pharmablock / 4567-tetrahydropyrazolo[15-a]pyridine-2-carboxylic acid / 25mg / 587659398 / PBT1832 / 0.000 / 307313-03-7 / MFCD09056814 / 166.180 / C8H10N2O2
Pharmablock / 4567-tetrahydropyrazolo[15-a]pyridine-2-carboxylic acid / 25mg / 587659398 / PBT1832 / 0.000 / 307313-03-7 / MFCD09056814 / 166.180 / C8H10N2O2
Frontier Specialty Chemicals 1G 1-METHYL-5-(TRIFLUOROMETHYL
1-Methyl-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid; CAS: 119083-00-0; 1g